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Home / Primary Antibodies / Monoclonal Antibodies

Anti-c-Myb Oncoprotein Antibody BHA10203571

SKU : BHA10203571

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NeoBiotechnologies, Inc.

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Mfr.No.	4602-MSM1-P1ABX
Alternative Names	c-myb_CDS ; efg ; ONCOGENE AMV ; Oncogene MYB ; Proto-oncogene c-Myb ; Transcriptional activator Myb ; v-myb avian myeloblastosis viral oncogene homolog
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	6q23.3
Clonality	Monoclonal
Description	The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
Host	Mouse
Immunogen	A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb oncoprotein, coupled to KLH
Isotype	IgG1 Kappa
Positive Control	Jurkat, MOLT-4, COLO or BT-20 cells. Colon or breast carcinomas.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01104
Uniprot	606320
Gene Id	4602

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203571	4602-MSM1-P1ABX	100µg	$393.20		Add to Cart

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