Anti-Ep-CAM / CD326 Antibody BHA10203114

Mfr.No.	4072-MSM6-P1ABX
Alternative Names	Adenocarcinoma-associated Antigen ; Cell Surface Glycoprotein Trop-1 ; EGP2 ; EGP314 ; EGP40 ; Epithelial Cell Adhesion Molecule ; Epithelial Glycoprotein 314 ; ESA ; KSA ; TACD1
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	2q21
Clonality	Monoclonal
Description	Recognizes a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
Host	Mouse
Immunogen	A synthetic peptide (around aa 20-60) from the N-terminus of human TACSTD1 protein
Isotype	IgG1 Kappa
Positive Control	HT29 cells or breast tumor
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P16422
Uniprot	542050
Gene Id	4072

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F, CO-IF

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.

, FACS ; IF ; WB ; IHC-F ; co-if

Dilution