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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD46 (Membrane Cofactor Protein) Antibody BHA10203226

SKU : BHA10203226

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NeoBiotechnologies, Inc.

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Mfr.No.	4179-MSM2-P1ABX
Alternative Names	AHUS2 ; Complement membrane cofactor protein ; MCP ; Measles virus receptor ; Membrane cofactor protein ; MIC10 ; TLX ; Trophoblast leucocyte common antigen ; Trophoblast lymphocyte cross reactive antigen
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	1q32
Clonality	Monoclonal
Description	Recognizes a protein of 52kDa-58kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.
Host	Mouse
Immunogen	Stimulated human leukocytes
Isotype	IgG2a Kappa
Positive Control	K562, U937, HL60, HeLa and Jurkat cells, and human lymphocytes. Lymph node and tonsil.
Reactivity	Human, Baboon
Recombinant	FALSE
Regulatory	RUO

Swissprot	P15529
Uniprot	510402
Gene Id	4179

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203226	4179-MSM2-P1ABX	100µg	$393.20		Add to Cart

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