72kD type IV collagenase ; CLG4A ; Collagenase Type 4 alpha ; Collagenase type IV A ; Gelatinase A ; Gelatinase alpha ; Gelatinase neutrophil ; Matrix metalloproteinase-2 ; MMP2 ; MONA
Categories
Primary Antibodies
Cellular Localization
Cell Surface, Cytoplasmic
Chromosome Location
16q12.2
Clonality
Monoclonal
Description
It recognizes a protein of 72kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
Host
Mouse
Immunogen
Recombinant human MMP2 protein fragment (aa444-575) (exact sequence is proprietary)
Isotype
IgG1
Positive Control
U-138 MG or U-87 MG cells. Placenta
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P08253
Uniprot
513617
Gene Id
4313
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, WB
Description
Optimal dilution for a specific application should be determined., FACS ; IF ; WB
Dilution
FACS
0.5-1μg/million cells
IF
0.5-1μg/ml
WB
0.5-1μg/ml
Reviews of Anti-MMP2 / Collagenase Type IV A Antibody BHA10203331