Anti-MCM7 Antibody BHA10203210

Mfr.No.	4176-MSM4-P1ABX
Alternative Names	CDC47 ; DNA replication licensing factor MCM7 ; MCM7 mini chromosome maintenance deficient 7 ; Mini chromosome Maintenance 7 ; Mini chromosome maintenance protein 7 ; P1.1-MCM3 ; P1CDC47 ; P85MCM ; PNAS146
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	7q21.3-q22.1
Clonality	Monoclonal
Description	MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
Host	Mouse
Immunogen	Recombinant human MCM7 protein fragment (aa195-319) (exact sequence is proprietary)
Isotype	IgG2b Kappa
Positive Control	Raji or Ramos cells. Tonsil
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P33993
Uniprot	438720
Gene Id	4176

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203210	4176-MSM4-P1ABX	100µg	$393.20		Add to Cart

Anti-MCM7 Antibody BHA10203210

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