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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD171 / NCAM-L1 Antibody BHA10202974

SKU : BHA10202974

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NeoBiotechnologies, Inc.

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Mfr.No.	3897-MSM1-P1ABX
Alternative Names	CAML1 ; HSAS1 ; Hyd ; L1 Cell Adhesion Molecule ; L1-NCAM ; MASA ; MIC5 ; NCAM-L1 ; Nerve-growth factor-inducible large external glycoprotein ; Neural cell adhesion molecule L1
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	Xq28
Clonality	Monoclonal
Description	Recognizes a cell surface protein of 220-240kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
Host	Mouse
Immunogen	Homogenous suspension of 16 week human fetal brain
Isotype	IgG1 Kappa
Positive Control	Neuroblastomas or Schwannomas
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P32004
Uniprot	52818
Gene Id	3897

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202974	3897-MSM1-P1ABX	100µg	$393.20		Add to Cart

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