ABC29 ; ABCC1 ; ATP binding cassette sub family C (CFTR/MRP) member 1 ; ATP-binding cassette sub-family C member 1 ; GSX ; Leukotriene C(4) transporter ; LTC4 transporter ; Multidrug resistance-associated protein 1 (MRP1)
Categories
Primary Antibodies
Cellular Localization
Cell Surface, Cytoplasmic
Chromosome Location
16p13.11
Clonality
Monoclonal
Description
The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.
Host
Mouse
Immunogen
Recombinant human full-length ABCC1
Isotype
IgG2a
Positive Control
A549 cells. Colon, Endometrium, Ovary. Testis or Tonsil.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P33527
Uniprot
391464
Gene Id
4363
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, WB
Description
Optimal dilution for a specific application should be determined., FACS ; IF ; WB
Dilution
FACS
0.5-1μg/million cells
IF
0.5-1μg/ml
WB
0.5-1μg/ml
Reviews of Anti-MRP1 / ABCC1 (Multidrug Resistance Related Protein 1) Antibody BHA10203341