Anti-MAGE-1 (Target for Cancer Immunotherapy) Antibody BHA10203155

Mfr.No.	4100-MSM1X-P1ABX
Alternative Names	MZ2 E ; cancer/testis antigen 1.1 ; CT1.1 ; MAGE1A ; MAGEA1 ; Melanoma antigen family A 1 ; Melanoma associated antigen 1 ; Melanoma associated antigen MZ2 E
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	Xq28
Clonality	Monoclonal
Description	Recognizes a protein of 42-46kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
Host	Mouse
Immunogen	Human MAGE-A1 full length recombinant protein
Isotype	IgG1 Kappa
Positive Control	Melanoma cell lines. Melanomas, gliomas, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, and renal cell carcinomas.
Reactivity	Human, Rat, Dog
Recombinant	FALSE
Regulatory	RUO

Swissprot	P43355
Uniprot	72879
Gene Id	4100

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203155	4100-MSM1X-P1ABX	100µg	$393.20		Add to Cart

Anti-MAGE-1 (Target for Cancer Immunotherapy) Antibody BHA10203155

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