Cell Proliferation-inducing Gene 46 Protein ; CK18 ; CYK18 Cytokeratin Endo B ; K18 ; Keratin-18 ; Kerd ; KRT18
Categories
Primary Antibodies
Cellular Localization
Cytoplasmic
Chromosome Location
12q13.13
Clonality
Monoclonal
Description
This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Host
Mouse
Immunogen
Recombinant full-length human KRT18 protein
Isotype
IgG
Positive Control
MCF-7, HeLa, A431 cells or Breast Cancer
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P05783
Uniprot
406013
Gene Id
3875
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F
Dilution
FACS
0.5-1μg/million cells in 0.1ml
IF
1-2μg/ml
IHC-F
0.5-1μg/ml for 30 min at RT
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Reviews of Anti-Cytokeratin 18 (KRT18) Antibody BHA10202909