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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD104 (Integrin Beta-4) (Squamous Cell Carcinoma Antigen) Antibody BHA10202522

SKU : BHA10202522

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NeoBiotechnologies, Inc.

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Mfr.No.	3691-MSM1-P1ABX
Alternative Names	GP150 ; Integrin beta-4 ; ITGB4
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	17q25.1
Clonality	Monoclonal
Description	Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alteatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Host	Mouse
Immunogen	Human squamous cell carcinoma (UM-SCC1)
Isotype	IgG2a Kappa
Positive Control	A431 cells, squamous cell carcinoma, colon or placenta
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P16144
Uniprot	632226
Gene Id	3691

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Biological Blockade (Partially blocks laminin binding) (Order Ab without Azide);Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202522	3691-MSM1-P1ABX	100µg	$393.20		Add to Cart

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