CD11 antigen-like family member C ; Complement component 3 receptor 4 subunit ; Integrin alpha-X ; integrin, alpha X (antigen CD11C (p150), alpha polypeptide) ; Leu M5 alpha subunit ; Leukocyte adhesion glycoprotein p150 95 alpha chain ; Myeloid membrane antigen alpha subunit ; p150/95
Categories
Primary Antibodies
Cellular Localization
Cell Surface
Chromosome Location
16p11.2
Clonality
Monoclonal
Description
CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
Host
Mouse
Immunogen
Human monocytic U937 phorbol ester-treated cells
Isotype
IgG1 Kappa
Positive Control
Human dendritic cells. Human lymph nodes and tonsils.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P20702
Uniprot
248472
Gene Id
3687
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, Func
Description
Optimal dilution for a specific application should be determined., FACS ; IF ; Func