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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD11b / MAC-1 Antibody BHA10202477

SKU : BHA10202477

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NeoBiotechnologies, Inc.

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Mfr.No.	3684-RTM2-P1ABX
Alternative Names	CD11 antigen-like family member B ; CD11b/CD18 ; CD49d ; Cell surface glycoprotein MAC-1 subunit alpha ; Complement Component Receptor 3 Alpha ; CR3 Alpha Chain (CR3A) ; Integrin alpha-M ; Integrin beta 2 alpha subunit ; ITGAM ; Leukocyte adhesion receptor MO1
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	16p11.2
Clonality	Monoclonal
Description	CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin �M combines with the Integrin ?2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin �M/?2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. The protein CD11b has been implicated in the various adhesion-related interactions of cells such as monocytes, macrophages, natural killer (NK) cells, and granulocytes. It is part of a heterodimer that consists of CD11b and CD18. It also modulates the uptake of complement-coated particles within the cell. It is commonly used as a microglial marker in tissues derived from the nervous system.
Host	Rat
Immunogen	B10 mouse spleen cells enriched for T lymphocytes
Isotype	IgG2b Kappa
Positive Control	Monocytes & granulocytes. Lymph nodes and tonsils.
Reactivity	Human, Chimpanzee, Baboon, Cynomolgus, Rhesus, Rabbit, Mouse
Recombinant	FALSE
Regulatory	RUO

Swissprot	P11215
Uniprot	172631
Gene Id	3684

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, Func

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; Func

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
Func	Order Ab without BSA & Azide

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202477	3684-RTM2-P1ABX	100µg	$393.20		Add to Cart

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