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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD18 / Integrin beta-2 (ITGB2) Antibody BHA10202502

SKU : BHA10202502

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NeoBiotechnologies, Inc.

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Mfr.No.	3689-MSM1-P1ABX
Alternative Names	Beta 2 (antigen CD18 (p95) ; CD18 ; Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta ; Cell surface adhesion glycoproteins LFA-1/CR3/p150 ; Complement component 3 receptor 3 and 4 subunit ; Complement receptor C3 beta subunit ; Integrin beta-2 (ITGB2) ; LAD ; LCAMB ; Leukocyte Cell Adhesion Molecule CD18
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	21q22.3
Clonality	Monoclonal
Description	It recognizes a transmembrane glycoprotein of 95kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This MAb blocks these cellular interactions.
Host	Mouse
Immunogen	Stimulated human leukocytes
Isotype	IgG2a Kappa
Positive Control	Lymphocytes, granulocytes, and macrophages in tonsil or lymph node.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P05107
Uniprot	375957
Gene Id	3689

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Functional Studies (Order Ab without Azide); Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202502	3689-MSM1-P1ABX	100µg	$393.20		Add to Cart

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