Anti-Cytokeratin 15 (KRT15) Antibody BHA10202825

Mfr.No.	3866-MSM2-P1ABX
Alternative Names	CK15 ; Cytokeratin 15 ; K1CO ; Ka15 ; Keratin 15 basic ; Keratin 15 beta ; Keratin complex 1 acidic gene 15 ; Keratin type I cytoskeletal 15 ; KRT15 ; KRTB
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	17q21.2
Clonality	Monoclonal
Description	Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.
Host	Mouse
Immunogen	Recombinant human KRT15 protein
Isotype	IgG2a Kappa
Positive Control	A431 cells. Skin or Colon
Reactivity	Human, Rat, Cow
Recombinant	FALSE
Regulatory	RUO

Swissprot	P19012
Uniprot	654570
Gene Id	3866

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB, IHC-Ff

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-Ff

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
WB	0.5-1μg/ml
IHC-Ff	0.5-1.0μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202825	3866-MSM2-P1ABX	100µg	$393.20		Add to Cart

Anti-Cytokeratin 15 (KRT15) Antibody BHA10202825

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