Anti-Cytokeratin 10 (KRT10) Antibody BHA10202761

Mfr.No.	3858-MSM1X-P1ABX
Alternative Names	BCIE ; BIE ; EHK ; Keratin Type I Cytoskeletal 10 ; KRT10
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	17q21.2
Clonality	Monoclonal
Description	This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Host	Mouse
Immunogen	Skin extract of a human Psoriasis patient
Isotype	IgG1 Kappa
Positive Control	A431, HeLa, MCF7 cells or Esophagus.
Reactivity	Human, Mouse
Recombinant	FALSE
Regulatory	RUO

Swissprot	P13645
Uniprot	99936
Gene Id	3858

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-F	0.1-0.2μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202761	3858-MSM1X-P1ABX	100µg	$393.20		Add to Cart

Anti-Cytokeratin 10 (KRT10) Antibody BHA10202761

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