Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). The protein detectable is a complex of CD41 and CD61.The apparent molecular weight of the GPIIIa by SDS-PAGE is 105kDa reduced and 90kDa unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding.Ā
Host
Mouse
Immunogen
Normal blood mononuclear cells activated by mixed lymphocyte reaction
Isotype
IgM Kappa
Positive Control
U937, KG1a, HEL cells, and human platelets in lymph nodes or tonsils.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P05106
Uniprot
218040
Gene Id
3690
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, Inhibits platelet aggregation
Description
Optimal dilution for a specific application should be determined., FACS ; IF ; Inhibits platelet aggregation
Dilution
FACS
0.5-1μg/million cells in 0.1ml
IF
0.5-1μg/ml
Inhibits platelet aggregation
Order Ab without Azide
Reviews of Anti-CD61 / Integrin beta-3 Antibody BHA10202507