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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD25 / IL2RA Antibody BHA10202375

SKU : BHA10202375

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NeoBiotechnologies, Inc.

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Mfr.No.	3559-MSM1-P1ABX
Alternative Names	IL2 Receptor alpha ; IL2R alpha chain ; IL2R ; IL2R subunit alpha IL2RA ; Interleukin-2 receptor subunit alpha ; Ly43 ; p55 ; p55 chain ; T Cell Growth Factor Receptor ; TAC antigen
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	10p15-p14
Clonality	Monoclonal
Description	Recognizes a protein of 55kDa, identified as CD25 (Workshop IV; Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkinā€™s disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R ļ� � chain, p75) and CD132 (common ļ� � chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.
Host	Mouse
Immunogen	Stimulated human leukocytes
Isotype	IgG1 Kappa
Positive Control	PHA-stimulated human lymphocytes. Human lymph nodes and tonsils.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01589
Uniprot	231367
Gene Id	3559

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Functional Studies (Order Ab without Azide); Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202375	3559-MSM1-P1ABX	100µg	$393.20		Add to Cart

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