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Home / Primary Antibodies / Monoclonal Antibodies

Anti-HLA-B (MHC Class I) Antibody BHA10201800

SKU : BHA10201800

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NeoBiotechnologies, Inc.

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Mfr.No.	3106-MSM1-P0
Alternative Names	HLA-B, HLAB, MHC Class I HLA heavy chain, Leukocyte antigen class I-B
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	6p21.3
Clonality	Monoclonal
Description	HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Host	Mouse
Immunogen	Normal human peripheral blood lymphocytes
Isotype	IgG3 Kappa
Positive Control	Human peripheral blood lymphocytes, tonsil or lymph node
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01889
Uniprot	77961
Gene Id	3106

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

FACS, IF

Description

Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201800	3106-MSM1-P0	20µg	$204.67		Add to Cart
BHA10201800	3106-MSM1-P0	100µg	$393.20		Add to Cart

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