HLA-A ; HLA-B ; HLA-C ; HLA class 1A ; HLA class 1B ; HLA class 1C ; Major histocompatibility complex, class I, A + B + C ; MHC class I HLA-A ; MHC class I HLA-B ; MHC class I HLA-C
Categories
Primary Antibodies
Cellular Localization
Cell Surface
Chromosome Location
6q21.3
Clonality
Monoclonal
Description
Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
Host
Mouse
Immunogen
Human peripheral blood leukocytes
Isotype
IgG2a Kappa
Positive Control
THP-1 and Jurkat cells. Tonsil or lymph node.
Reactivity
Human, Mouse, non-human primates
Recombinant
FALSE
Regulatory
RUO
Swissprot
P01889; P30443; P30499
Uniprot
181244; 654404; 77961
Gene Id
3105;3106;3107
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF
Description
Optimal dilution for a specific application should be determined., FACS ; IF
Dilution
FACS
0.5-1μg/million cells in 0.1ml
IF
0.5-1μg/ml
Reviews of Anti-HLA-ABC (MHC I) Antibody BHA10201774