Anti-CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) Antibody BHA10201759

Mfr.No.	30835-MSM1-P1ABX
Alternative Names	CD209 ; CDSIGN ; CIRE ; CLEC4L ; DC-SIGN ; DC-SIGN1 ; DCSIGN ; Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1 ; HIV GP120 Binding Protein ; SIGN-R1
Categories	Primary Antibodies
Cellular Localization	Cell Surface(secreted)
Chromosome Location	19p13
Clonality	Monoclonal
Description	DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
Host	Mouse
Immunogen	Recombinant human CD209 protein fragment
Isotype	IgG2b Kappa
Positive Control	THP-1 or HeLa Cells. Small Intestine, Uterus or Lymph Node.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9NNX6
Uniprot	278694
Gene Id	30835

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Tris with 1mM EDTA Buffer, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201759	30835-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) Antibody BHA10201759

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