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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-IDH1 (Isocitrate Dehydrogenase) Antibody BHA10202049

SKU : BHA10202049

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NeoBiotechnologies, Inc.

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Mfr.No.	3417-RBP3-P1ABX
Alternative Names	Cytosolic NADP-isocitrate dehydrogenase ; Epididymis luminal protein 216 ; Epididymis secretory protein Li 26 ; HEL-216 ; HEL-S-26 ; ICDH ; IDCD ; IDH1 ; IDP ; IDPC
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Nuclear
Chromosome Location	2q33.3
Clonality	Polyclonal
Description	It recognizes a 45kDa protein, which is identified as isocitrate dehydrogenase (IDH1). It belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming Ī �-ketoglutarate and CO2 in a two-step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of Ī �-ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Recently, an inactivating mutation of IDH1 has been implicated in glioblastoma. IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.
Host	Rabbit
Immunogen	Recombinant fragment (119 Amino acid residues; aa 296-414) of human IDH1 protein
Isotype	Ig
Positive Control	HepG2, HeLa, HT29 or MCF7 cells. Breast, Colon or Prostate Carcinoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	O75874
Uniprot	593422
Gene Id	3417

Buffer	200μg/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; WB

Dilution

FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
WB	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202049	3417-RBP3-P1ABX	100µg	$393.20		Add to Cart

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