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Home / Primary Antibodies / Monoclonal Antibodies

Anti-HLA-A (MHC I) Antibody BHA10201779

SKU : BHA10201779

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NeoBiotechnologies, Inc.

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Mfr.No.	3105-MSM3-P1ABX
Alternative Names	HLA-A ; HLA class 1A ; MHC class I HLA-A
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	6q21.3
Clonality	Monoclonal
Description	HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. This MAb is useful for HLA molecular typing of peripheral blood leukocytes as well as a large number of leukemic cell lines. It reacts with an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, -A28, -A29, -A30, -A31 and �Aw33). Its epitope maps between aa65-to-aa80 of the ?1 domain of the HLA-A. This MAb recognizes an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, A28, -A29, -A30, -A31 and -Aw33). Furthermore, by testing its reactivity with HLA-A2 natural variants and mutants, the importance of amino acid residues 79 and/or 80 of the α1 domain was demonstrated in the formation of an intralocus HLA-A determinant.
Host	Mouse
Immunogen	Normal human peripheral blood lymphocytes
Isotype	IgG1 Kappa
Positive Control	THP-1 and Jurkat cells. Tonsil or lymph node.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01889; P30443; P30499
Uniprot	181244; 654404; 77961
Gene Id	3105;3106;3107

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201779	3105-MSM3-P1ABX	100µg	$393.20		Add to Cart

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