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Home / Primary Antibodies / IHC Antibodies

Anti-CD13 / Aminopeptidase-N Antibody BHA10201644

SKU : BHA10201644

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NeoBiotechnologies, Inc.

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Mfr.No.	290-MSM1-P1ABX
Alternative Names	Alanyl aminopeptidase ; Aminopeptidase M ; Aminopeptidase N ; ANPEP ; AP-M ; APN ; gp150 ; hAPN ; Lap1 ; Microsomal aminopeptidase
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	15q25-26
Clonality	Monoclonal
Description	Recognizes an integral membrane glycoprotein of 150kDa, identified as CD13 (also known as aminopeptidase-N). The CD13 antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. CD13 is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts; endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN), a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal/tumoricidal activities. It also serves as a receptor for human coronaviruses (HCV). The lineage-restricted pattern of expression of CD13 within the hemopoietic compartment suggests that it may be important in myeloid cell differentiation.
Host	Mouse
Immunogen	KG-1 myeloid cells
Isotype	IgG1 Kappa
Positive Control	Macrophages in a lymph node/tonsil or in any normal tissue.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P15144
Uniprot	1239
Gene Id	290

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201644	290-MSM1-P1ABX	100µg	$393.20		Add to Cart

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