Anti-AMP Deaminase, Isoform E (AMPD3) Antibody BHA10201549

Mfr.No.	272-MSM1-P1ABX
Alternative Names	Adenosine monophosphate deaminase (isoform E) ; AMP aminohydrolase ; AMP deaminase 3 ; AMP deaminase isoform E ; Ampd3 ; Erythrocyte AMP deaminase ; Erythrocyte specific AMP deaminase ; Erythrocyte specific protein ; Erythrocyte type AMP deaminase ; Myoadenylate deaminase
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	11p15.4
Clonality	Monoclonal
Description	It recognizes a protein of ~90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
Host	Mouse
Immunogen	Recombinant full-length human AMDP3 protein
Isotype	IgG2b Kappa
Positive Control	RBC. Fetal liver; Spleen or Placenta
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q01432
Uniprot	501890
Gene Id	272

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC ; IHC-F

Dilution

FACS	1-2μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC	1-2.0μg/ml for 30 minutes at RT
IHC-F	2-4μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201549	272-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-AMP Deaminase, Isoform E (AMPD3) Antibody BHA10201549

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