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Home / Primary Antibodies / Monoclonal Antibodies

Anti-TOX3 / TNRC9 Antibody BHA10201561

SKU : BHA10201561

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NeoBiotechnologies, Inc.

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Mfr.No.	27324-MSM2-P1ABX
Alternative Names	TOX3 ; CAG trinucleotide repeat-containing gene F9 protein ; CAGF9 ; TOX high mobility group box family member 3 ; Trinucleotide repeat containing 9 (TNRC9)
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Nuclear
Chromosome Location	16q12.1
Clonality	Monoclonal
Description	It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Host	Mouse
Immunogen	Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Isotype	IgG1 Kappa
Positive Control	SH-SY5Y, MDA-MB-435 cells. Brain or breast or gastric Carcinoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	O15405
Uniprot	460789
Gene Id	27324

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; WB

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
WB	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201561	27324-MSM2-P1ABX	100µg	$393.20		Add to Cart

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