Anti-Connexin 32 (Gap Junction Protein) Antibody BHA10201479

Mfr.No.	2705-MSM3-P1ABX
Alternative Names	Charcot Marie Tooth neuropathy X linked ; CMTX ; CMTX1 ; Connexin-32 ; Cx32 ; GAP junction 28kDa liver protein ; Gap junction beta-1 protein ; Gap junction protein beta 1 32kD ; GJB1
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	Xq13.1
Clonality	Monoclonal
Description	This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane α-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another.
Host	Mouse
Immunogen	Recombinant human GJB1 protein
Isotype	IgG
Positive Control	MCF-7 Cells. Liver, Kidney, Stomach or Tonsil
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P08034
Uniprot	333303
Gene Id	2705

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

IF, FACS, WB, IHC(fro)

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., IF ; FACS ; WB ; IHC(fro)

Dilution

IF	1-2μg/ml
FACS	0.5-1μg/million cells
WB	0.5-1μg/ml
IHC(fro)	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201479	2705-MSM3-P1ABX	100µg	$393.20		Add to Cart

Anti-Connexin 32 (Gap Junction Protein) Antibody BHA10201479

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