Anti-Alkaline Phosphatase (Placental) / PLAP Antibody BHA10201346

Mfr.No.	250-MSM5-P1ABX
Alternative Names	Alkaline phosphatase placental type ; Alkaline phosphatase Regan Isozyme ; ALP ; Alp1 ; ALPP ; Germ-cell alkaline phosphatase ; nagao Isozyme ; PALP ; Placental alkaline phosphatase 1 ; placental heat-stable alkaline phosphatase
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	2q37.1
Clonality	Monoclonal
Description	Reacts with a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.Ā
Host	Mouse
Immunogen	Purified human PLAP protein
Isotype	IgG2b Kappa
Positive Control	HepG2 cells. Placenta or seminoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P05187
Uniprot	284255
Gene Id	250

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-Ff

Description

(No special pretreatment is required for the immunohistochemical staining of formalin-fixed tissues.); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-Ff

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-Ff	0.25-0.5μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201346	250-MSM5-P1ABX	100µg	$393.20		Add to Cart

Anti-Alkaline Phosphatase (Placental) / PLAP Antibody BHA10201346

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