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Home / Primary Antibodies / IHC Antibodies

Anti-Alkaline Phosphatase (Placental) / PLAP Antibody BHA10201334

SKU : BHA10201334

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NeoBiotechnologies, Inc.

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Mfr.No.	250-MSM3-P1ABX
Alternative Names	Alkaline phosphatase placental type ; Alkaline phosphatase Regan Isozyme ; ALP ; Alp1 ; ALPP ; Germ-cell alkaline phosphatase ; nagao Isozyme ; PALP ; Placental alkaline phosphatase 1 ; placental heat-stable alkaline phosphatase
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	2q37.1
Clonality	Monoclonal
Description	PLAP is a tissue specific, trophoblast-derived, 70kDa, glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2+ metallo-glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific APā€™s in humans, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous. Non-tissue specific AP is found in kidney, liver and bone. This MAb binds equally well to all common allelic variants (S, F, FS and I) of PLAP and to some variants of AP from normal human testis. This MAb can be used as tracer antibody in ELISA to detect PLAP in serum of S, F, FS and I phenotypes.
Host	Mouse
Immunogen	Recombinant full-length human ALPP protein
Isotype	IgG1 Kappa
Positive Control	HepG2 cells. Placenta or seminoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P05187
Uniprot	284255
Gene Id	250

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201334	250-MSM3-P1ABX	100µg	$393.20		Add to Cart

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