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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-CELA3B / ELA3B Antibody BHA10201255

SKU : BHA10201255

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NeoBiotechnologies, Inc.

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Mfr.No.	23436-MSM4-P1ABX
Alternative Names	Chymotrypsin like elastase family member 3B (CELA3B) ; ELA3B ; Elastase IIIB ; Protease E
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	1p36.12
Clonality	Monoclonal
Description	This MAb recognizes a protein of ~30kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
Host	Mouse
Immunogen	Recombinant human CELA3B protein fragment (aa82-238) (exact sequence is proprietary)
Isotype	IgG3
Positive Control	Panc-28 or PANC1 cells. Pancreas
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P08861
Uniprot	728752
Gene Id	23436

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

ELISA, IF, FACS

Description

Optimal dilution for a specific application should be determined., ELISA ; IF ; FACS

Dilution

ELISA	Use Ab at 2-4μg/ml for coating
IF	0.5-1μg/ml
FACS	0.5-1μg/million cells

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201255	23436-MSM4-P1ABX	100µg	$393.20		Add to Cart

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