Anti-Protocadherin FAT2 (FAT Atypical Cadherin 2) Antibody BHA10201066

Mfr.No.	2196-MSM1-P1ABX
Alternative Names	FAT tumor suppressor homolog 2 (HFAT2) ; cadherin family member 8 (CDHF8) ; cadherin-related family member 9 (CDHR9) ; multiple EGF-like domains protein 1 ; multiple epidermal growth factor-like domains 1 (MEGF1) ; multiple epidermal growth factor-like domains protein 1 ; protocadherin FAT2.
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	5q33.1
Clonality	Monoclonal
Description	Recognizes a protein of 480kDa, which is identified as FAT2. The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development.
Host	Mouse
Immunogen	Purified recombinant human FAT2 fusion protein
Isotype	IgG1 Kappa
Positive Control	Esophagus, Cervix, Uterus, Tonsil or Cerebellum.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9NYQ8
Uniprot	591255
Gene Id	2196

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201066	2196-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-Protocadherin FAT2 (FAT Atypical Cadherin 2) Antibody BHA10201066

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