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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD16 / Fc-gamma Receptor III Antibody BHA10201091

SKU : BHA10201091

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NeoBiotechnologies, Inc.

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Mfr.No.	2214-MSM3-P1ABX
Alternative Names	FcRIIIa ; FCR-10 ; FcRIII ; FCGRIII ; FcR-10 ; Fc fragment of IgG, low affinity IIIa, receptor for (CD16) ; neutrophil-specific antigen NA ; CD16a ; low affinity immunoglobulin gamma Fc region receptor III-A ; Fc-gamma RIIIa
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	1q23
Clonality	Monoclonal
Description	Recognizes a protein of 50-65kDa, identified as CD16 (Workshop IV; Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This MAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.
Host	Mouse
Immunogen	Human peripheral blood lymphocytes from a NK-leukemia patient.
Isotype	IgG2a Kappa
Positive Control	K-562 or U-937 cells. Lymph nodes and tonsils.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P08637
Uniprot	372679
Gene Id	2214

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Functional Studies (Order Ab without BSA & Azide); Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201091	2214-MSM3-P1ABX	100µg	$393.20		Add to Cart

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