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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Endoglin / CD105 Antibody BHA10200927

SKU : BHA10200927

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NeoBiotechnologies, Inc.

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Mfr.No.	2022-MSM2-P1ABX
Alternative Names	CD105 ; END ; Endoglin ; Eng ; HHT1 ; S-endoglin
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	9q34.11
Clonality	Monoclonal
Description	CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for Prostate Adenocarcinoma, and cancers of the lung, stomach, breast, and brain.
Host	Mouse
Immunogen	Recombinant human Endoglin protein fragment (aa74-251) (exact sequence is proprietary)
Isotype	IgG1
Positive Control	HeLa, A431 and HL-60 cells. Colon.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P17813
Uniprot	76753
Gene Id	2022

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA at 1.0mg/ml

Applications

FACS, IF, WB

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; WB

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
WB	1-2μg/ml for 60 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200927	2022-MSM2-P1ABX	100µg	$393.20		Add to Cart

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