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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Desmoglein-1 (DSG1) Antibody BHA10200761

SKU : BHA10200761

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NeoBiotechnologies, Inc.

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Mfr.No.	1828-MSM1-P1ABX
Alternative Names	Cadherin family member 4 ; CDHF4 ; Desmoglein-1 ; Desmosomal glycoprotein 1 ; DG1 ; DSG1 ; EPKHE ; EPKHIA ; Pemphigus foliaceus antigen ; PPKS1
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	18q12.1
Clonality	Monoclonal
Description	Recognizes a protein of ~150kDa, identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
Host	Mouse
Immunogen	Human desmoglein-1 intracellular domain (exact sequence is proprietary)
Isotype	IgG1 Kappa
Positive Control	A431 or A-375 cells. Skin
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q02413
Uniprot	2633
Gene Id	1828

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; WB

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
WB	0.5-1.0μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200761	1828-MSM1-P1ABX	100µg	$393.20		Add to Cart

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