Clathrin heavy chain ; Clathrin heavy chain 1 ; Clathrin heavy chain 2 ; Clathrin heavy chain on chromosome 17 (CHC17 or CHC-17) ; CLH22 ; CLTC ; CLTCL ; CLTCL1 ; CLTCL2 ; CLTD
Categories
Primary Antibodies
Cellular Localization
Cytoplasmic
Chromosome Location
17q23.1
Clonality
Monoclonal
Description
Recognizes protein of 192kDa, which is identified as Clathrin Heavy Chain. Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain-binding site. The proximal segment of the Clathrin HC protein is essential for interactions between Clathrin heavy chains and light chains, which result in the formation of the triskelion structure.
Host
Mouse
Immunogen
Purified recombinant N-terminal fragment of human Clathrin Heavy Chain (exact sequence is proprietary)
Isotype
IgG1 Kappa
Positive Control
HeLa cells. Placenta or Prostate Carcinoma.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P53675 and Q00610
Uniprot
491351
Gene Id
1213
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, WB
Description
Optimal dilution for a specific application should be determined., FACS ; IF ; WB
Dilution
FACS
0.5-1μg/million cells
IF
1-2μg/ml
WB
0.5-1μg/ml
Reviews of Anti-Clathrin, Heavy Chain Antibody BHA10200512