Anti-Catenin, beta (p120) Antibody BHA10200653

Mfr.No.	1499-MSM5-P1ABX
Alternative Names	Cadherin associated protein ; beta 1 88kDa ; Catenin beta-1 ; CATNB ; CHBCAT ; CTNNB1
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	3p22.1
Clonality	Monoclonal
Description	This MAb recognizes a protein of 92kDa, which is identified as beta-catenin. It shows no cross-reaction with gamma-catenin (also known as plakoglobin). The catenins, alpha, beta and gamma bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin was initially described as an E-cadherin-associated protein, and has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin has also been found in complexes with the tumor suppressor protein APC.
Host	Mouse
Immunogen	Recombinant chicken ?-catenin
Isotype	IgG1 Kappa
Positive Control	HeLa or MCF-7 cells. Breast carcinoma
Reactivity	Human, Cow, Dog, Chicken
Recombinant	FALSE
Regulatory	RUO

Swissprot	P35222
Uniprot	476018
Gene Id	1499

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA at 1.0mg/ml

Applications

FACS, IF, WB, IHC(ap)

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC(ap)

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
WB	0.5-1μg/ml
IHC(ap)	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200653	1499-MSM5-P1ABX	100µg	$393.20		Add to Cart

Anti-Catenin, beta (p120) Antibody BHA10200653

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