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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-CD195 (CC-Chemokine Receptor 5) Antibody BHA10200537

SKU : BHA10200537

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NeoBiotechnologies, Inc.

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Mfr.No.	1234-MSM1-P1ABX
Alternative Names	CC Chemokine Receptor Type 5 ; CC-CKR-5 ; CCCKR5 ; CCR5 ; Chemokine CC motif receptor 5 ; Chemokine receptor CCR5 ; CHEMR13 ; CKR5 ; CMKBR5 ; HIV-1 fusion coreceptor
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	3q21.31
Clonality	Monoclonal
Description	Reacts with the N-terminal extracellular domain of CD195. The CC chemokine receptor 5 (CCR5) is a member of the CC-chemokine receptor family, and has the characteristic structure of a 7 transmembrane G protein-coupled receptor (GPCR). CCR5 regulates trafficking and effector functions of memory/effector Th1 cells, macrophages, NK cells, and immature dendritic cells. CCR5 and its ligands play an important role in viral pathogenesis. CCR5 represents the co-receptor for macrophage (M) and dual (T cell and M)-tropic immunodeficiency viruses. Together with the CD4 binding receptor, CCR5 plays a critical role in HIV entry into the target cells. Moreover, the CCR5 ligands macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and RANTES act as endogenous inhibitors of HIV infection, making both CCR5 and its chemokine ligands attractive therapeutic targets for HIV infection. Recent studies have also highlighted the role of CCR5 in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
Host	Mouse
Immunogen	Human native CCR5 protein
Isotype	IgG2a Kappa
Positive Control	Human lymph node and tonsil.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P51681
Uniprot	450802
Gene Id	1234

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, Func, IHC(fro)

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; Func ; IHC(fro)

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
Func	Order Ab without BSA & Azide
IHC(fro)	0.5-1.0μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200537	1234-MSM1-P1ABX	100µg	$393.20		Add to Cart

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