COLL4 ; Collapsin4 ; GR3 ; M sema G ; MSEMA ; SEMA4D ; Semacl2 ; SemaH ; SEMAJ ; Semaphorin C like 2
Categories
Primary Antibodies
Cellular Localization
Cell Surface
Chromosome Location
9q22.2
Clonality
Monoclonal
Description
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
Host
Mouse
Immunogen
PHA stimulated human peripheral blood lymphocytes
Isotype
IgG1 Kappa
Positive Control
Daudi, Raji, HUT-78, Kg1a, U937, and human lymphocytes. Human tonsils and lymph nodes.
Reactivity
Human, Monkey, Mouse
Recombinant
FALSE
Regulatory
RUO
Swissprot
Q92854
Uniprot
494406
Gene Id
10507
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, Func
Description
Functional Studies (Order Ab without Azide); Optimal dilution for a specific application should be determined., FACS ; IF ; Func
Dilution
FACS
0.5-1μg/million cells in 0.1ml
IF
0.5-1μg/ml
Func
Order Ab without Azide
Reviews of Anti-CD100 (Semaphorin-4D) Antibody BHA10200256