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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD257 / BAFF / TNFSF13B Antibody BHA10200271

SKU : BHA10200271

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NeoBiotechnologies, Inc.

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Mfr.No.	10673-MSM1-P1ABX
Alternative Names	ApoL related ligand TALL 1 ; B lymphocyte stimulator ; B-cell-activating factor ; BAFF ; BLyS ; CD257 ; Dendritic cell-derived TNF-like molecule ; DTL ; PRO738 ; TALL-1
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	13q32-q34
Clonality	Monoclonal
Description	BAFF/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-γ and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).
Host	Mouse
Immunogen	Purified recombinant human full-length CD257 protein
Isotype	IgG1
Positive Control	Jurkat cells. Tonsil and lymph node
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9Y275
Uniprot	525157
Gene Id	10673

Buffer	200μg/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA at 1.0mg/ml

Applications

FACS, IF

Description

Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200271	10673-MSM1-P1ABX	100µg	$393.20		Add to Cart

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