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Home / Primary Antibodies / Monoclonal Antibodies

Anti-NDRG1 Antibody BHA10200148

SKU : BHA10200148

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NeoBiotechnologies, Inc.

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Mfr.No.	10397-MSM1-P1ABX
Alternative Names	GC4 ; cap43 ; cmt4d ; Differentiation-related gene 1 protein ; DRG-1 ; Hmsnl ; Human mRNA for RTP complete cds ; N-myc downstream-regulated gene 1 protein ; NDRG1 ; Nickel-specific induction protein Cap43
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	8q24.3
Clonality	Monoclonal
Description	It recognizes a protein of 43kDa, which is identified as N-myc downstream-regulated gene 1 protein (NDRG1). The NDRG) family is comprised of four members, NDRG1, NDRG2, NDRG3 and NDRG4, which share 57-65% homology. The NDRG1 gene is ubiquitously expressed, but it is expressed most prominently in placental membranes and prostate, kidney, small intestine and ovary tissue. NDRG1 is a direct transcriptional target gene of p53 to mediated cell death and apoptosis. NDRG1 gene expression is induced by several compounds, including nickel, and produces a protein involved in stress responses, hormone responses, cell growth and differentiation. The reduced expression of NDRG1 has been found to be associated with tumor metastasis in a variety of tumors, including cancers of the breast, colon, prostate, oral cavity and oropharynx. Reportedly, overexpression of NDRG1 in hepatocellular carcinoma is an indicator of tumor aggressiveness.
Host	Mouse
Immunogen	Recombinant fragment of human NDRG1 fragment (aa162-283) (exact sequence is proprietary)
Isotype	IgG3
Positive Control	HeLa Cells. Prostrate or Renal Carcinoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q92597
Uniprot	372914
Gene Id	10397

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; WB

Dilution

FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
WB	0.5-1.0μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200148	10397-MSM1-P1ABX	100µg	$393.20		Add to Cart

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