Anti-Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody BHA10200040

Mfr.No.	1014-MSM4-P1ABX
Alternative Names	Cadherin-16 (CDH16) ; Kidney-specific cadherin ; Ksp-cadherin antibody
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	16q22.1
Clonality	Monoclonal
Description	This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Host	Mouse
Immunogen	Recombinant full-length human CDH16 protein
Isotype	IgG1 Kappa
Positive Control	Normal kidney or renal cell carcinoma.
Reactivity	Human, Mouse, Rabbit, Dog, Rat
Recombinant	TRUE
Regulatory	RUO

Swissprot	O75309
Uniprot	513660
Gene Id	1014

Buffer	200μg/ml of recombinant MAb purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA buffer, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200040	1014-MSM4-P1ABX	100µg	$393.20		Add to Cart

Anti-Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody BHA10200040

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