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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-N-Cadherin / Cadherin-2 / CD325 (NCAD) Antibody BHA10200003

SKU : BHA10200003

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NeoBiotechnologies, Inc.

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Mfr.No.	1000-MSM1-P1ABX
Alternative Names	Cadherin-2 N cadherin neuronal ; Cadherin-2 type 1 ; Cadherin-2 ; Calcium dependent adhesion protein neuronal ; CD325 ; CDH2 ; CDHN ; CDw325 ; N-Cadherin ; NCAD
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	18q11.2
Clonality	Monoclonal
Description	Recognizes a protein of ~140kDa, identified as N-Cadherin (NCAD), also known as CD325. NCAD is a member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently deregulated in cancer cells. Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned on N-cadherin as opposed to E- or P-cadherin.
Host	Mouse
Immunogen	Recombinant human N-cadherin cytoplasmic domain (exact sequence is proprietary)
Isotype	IgG1 Kappa
Positive Control	HeLa or HUVEC cells. Heart, Pancreas or Cerebral Cortex
Reactivity	Human, Mouse
Recombinant	FALSE
Regulatory	RUO

Swissprot	P19022
Uniprot	464829
Gene Id	1000

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; WB

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
WB	0.5-1.0μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200003	1000-MSM1-P1ABX	100µg	$393.20		Add to Cart

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