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Home / Primary Antibodies / Conjugated Primary Antibodies

Anti-p44/42 MAPK Antibody (ERK12T202Y204-A11) FITC BHA10600053

SKU : BHA10600053

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Abwiz Bio Inc.

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Mfr.No.	1113
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	monoclonal
Description	MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. The p44/42 MAPK (Erk1/2) are members of mitogen-activated kinases (MAPKs) of serine/threonine protein kinases. Phospho ERK1/2 can be activated by a range of extracellular stimuli, such as mitogen, growth factors, neurotransmitters, chemokines, and cytokines, through receptor tyrosine kinases (RTK), G protein-coupled receptors (GPCRs), or protein kinase C (PKC). Upstream MEK1 and MEK2 activate p44 and p42 (phospho ERK1/2) through phosphorylation of activation loop residues Thr202/Tyr204 and Thr185/Tyr187, respectively. p44/42 (ERK1/2) are negatively regulated by a family of dual-specificity (Thr/Tyr) MAPK phosphatases, known as DUSPs or MKPs, along with MEK inhibitors, such as U0126 and PD98059.
Host	Rabbit
Immunogen	A synthetic phospho-peptide corresponding to residues surrounding Thr202/Tyr204 of human phospho Erk1/2.
Isotype	IgG1 Kappa
Modification	phospho-Erk1/2
Reactivity	Mouse, Human
Reregulatory	RUO

Clone No	ERK12T202Y204-A11

Buffer	1X PBS, 0.09% NaN3, 0.2% BSA
Storage	2-8ºC

Applications	FACS
Description	FACS

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SKU	Supplier No.	Size	Your price	Quantity
BHA10600053	1113	100Tests	$320.67		Add to Cart
BHA10600053	1113	10Tests	$120.67		Add to Cart

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