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Home / Primary Antibodies / Phospho Antibodies

Anti-BAD Antibody (BADS112-B9) Unconjugated BHA10600024

SKU : BHA10600024

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Abwiz Bio Inc.

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Mfr.No.	2246
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	monoclonal
Description	BAD is a distant member of the BCL-2 family, which regulate cell survival and apoptosis (1). Survival factors, such as IL-3, inhibit BAD's apoptotic activity by activating intracellular signaling pathways that result in the phosphorylation of BAD at Ser112 and Ser136 (1). S112/S136-phosphorylated phospho BAD binds to 14-3-3 proteins, sequestering phospho BAD in the cytosol and preventing association with Bcl-xL (1). Ser112 of BAD is phosphorylated both in vitro and in vivo by p90-RSK (2) and by mitochondria-anchored protein kinase A (3), while Ser136 of BAD is phosporylated by Akt to promote cell survival (4,5).
Host	Rabbit
Immunogen	A synthetic phospho-peptide corresponding to residues surrounding Ser112 of human phospho BAD
Isotype	IgG1 Lambda
Modification	phospho-Ser112
Reactivity	Mouse, Human
Reregulatory	RUO

Clone No	BADS112-B9

Buffer	1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
Concentration	0.5mg/ml
Dilutions	1.0 - 0.1 µg/ml
Storage	-20ºC

Applications	FACS
Description	FACS

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SKU	Supplier No.	Size	Your price	Quantity
BHA10600024	2246	200µl	$466.50		Add to Cart
BHA10600024	2246	20µl	$196.67		Add to Cart

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