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Home / Antibodies

FKBP12 Antibody / FKBP1A (F54946)

SKU : BHA17103406

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NSJ Bioreagents

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Mfr.No.	F54946, F54946-0.08ML, F54946-0.4ML
Antigen	FKBP12
Clonality	Polyclonal
Description	FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 55-83 from the human protein was used as the immunogen for the FKBP1A antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cytoplasmic

Uniprot	P62942

Format	Purified
Purification	Purified
Storage	Aliquot the FKBP1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	FACS, WB, IHC-P
Dilution	Flow cytometry: 1:10-1:50 (1x10e6 cells), Western blot: 1:500-1:1000, Immunohistochemistry (FFPE): 1:50-1:100

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17103406-1	F54946-0.08ML	0.08ml	$165		Add to Cart
BHA17103406-2	F54946-0.4ML	0.4ml	$379		Add to Cart

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