JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Fish Probe

eFISH NMYC/2Q11 Dual Color Probe

SKU : BHR15100120

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

BioGenex Laboratories

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	FP043-10X
Gene Name	NMYC/ 2q11
Fluorophore	Orange/Green
Chromosome	2
Intended Use	The BioGenex eFISH NMYC/2q11 Dual Color probeis currently available for Research use only.eFISH NMYC/2q11 Dual Color probe is designed to be used for the detection of the human NMYC gene as well as chromosome 2 specific sequences in formalinfixed, paraffin-embedded tissue or cells by fluorescence in situ hybridization (FISH). BioGenex eFISH NMYC/2q11 Dual Color probe comes in hybridization buffer. The probe contains green-labeled polynucleotides (Green: excitation at 503 nm and emission at 528 nm, similar to FITC), which target the NMYC gene, and orange-labeled polynucleotides (Orange:excitation at 547 nm and emission at 572 nm, similar to rhodamine), which target sequences of chromosome 2 in the chromosomal region 2q11
Description	Fluorescence in situ hybridization (FISH) is a robust technique of cytogenetic used for the detection of chromosomal aberrations, presence or absence of specific DNA sequence in native context. In this technique florescent probes bind to the target sequence of DNA in chromosome. High specificity and sensitivity coupled rapid and an accurate result has proven role of FISH in both research and diagnosis of solid tumor and hematological malignancies. As technique of cancer cytogenetics, FISH, can be used to identify genetic aberrations viz., deletions, amplification and translocation in tissue sections or within individual cells. FISH is also used for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific RNA targets in cells, circulating tumor cells, and tissue samples1,2,3,4,5. In FISH procedure, fixed tissue sections are pretreated to expose target DNA or mRNA sequences. An appropriately labeled probe is hybridized to the exposed target DNA or mRNA sequences in the cells. Subsequent stringent washing steps remove any probe that is non-specifically bound to the tissue section. Subsequently slides are mounted using DAPI/antifade and can be visualized under fluorescence microscope using appropriate filter set.
Principle	In Situ hybridization (ISH) allows the detection and localization of definitive nucleic acid sequences directly within a cell or tissue. High specificity is ensured through the action of annealing of fluorescence probe nucleic acid sequence to complementary target nucleic acid sequence. ISH techniques can be used to identify genetic aberrations like deletions, amplification, and translocationin tissue sections or within individual cells.
Storage	The BioGenex eFISH NMYC/2q11 Dual Color Probe must be stored at 2-8°C protected from light and is stable through the expiry date printed on the label.

Reference	Datasheet SDS

No Description Available.

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHR15100120	FP043-10X	10 tests	$1152		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.