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Home / Antibodies

Fas Antibody / CD95 (F54056)

SKU : BHA17119951

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NSJ Bioreagents

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Mfr.No.	F54056-0.1ML
Clonality	Monoclonal (mouse origin)
Description	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). (UniProt)
Formulation	Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Host	Mouse
Immunogen Region	A human recombinant protein was used as the immunogen for this Fas antibody.
Isotype	Mouse lgG2b
Species Reactivity	Human, Rat
Note	The stated application concentrations are suggested starting points. Titration of the Fas antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	P25445

Format	Purified
Purity	Protein G affinity
Storage	Store the Fas antibody at -20oC.

Applications	WB
Description	Western blot: 1:1000

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119951	F54056-0.1ML	0.1 ml	$379		Add to Cart

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