Erythropoietin / EPO is a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. It is the primary factor responsible for regulating erythropoiesis during steady-state conditions and in response to blood loss and hemorrhage in the adult organism. Erythropoietin is synthesized by the kidney and stimulates the proliferation and maturation of bone marrow erythroid precursor cells. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
A human partial recombinant protein was used as the immunogen for the Erythropoietin antibody.
Isotype
Mouse IgG1, kappa
Species Reactivity
Human
Note
Titering of the Erythropoietin antibody may be required for optimal performance.
Uniprot
P01588
Format
Purified
Purity
Protein G affinity chromatography
Storage
Store the Erythropoietin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Applications
ELISA, IHC-P
Description
ELISA: 2-4ug/ml (order BSA/azide-free format),Immunohistochemistry (FFPE): 2-4ug/ml for 30 min at RT