Human TIM-1/KIM-1/HAVCR Elisa Kit

Mfr.No.	SEKH-0320
Antigen	T Cell Immunoglobulin Mucin-1
Alternative Names	CD365; HAVCR1; HAVCR-1; KIM1; KIM-1; TIM1; TIM-1;
Background	TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
Categories	ELISA
Assay Length	3.5h
Detection Range	15.6-1,000 pg/ml
Sample Type	Serum, Plasma, Cell culture supernatant
Sensitivity	7 pg/ml

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SKU	Supplier No.	Size	Your price	Quantity
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