Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter (By similarity). May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells.
Specificity
Natural and recombinant Rat Zinc transporter 8
Subcellular Location
Cell membrane Multi-pass membrane protein Cytoplasmic vesicle secretory vesicle membrane Multi-pass membrane protein Associated with insulin and glucagon secretory granules.