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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Zinc finger E-box-binding homeobox 1

SKU : BHE13811214

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14970r
Alternative Names	Transcription factor 8 ; TCF-8 ; Zinc finger homeodomain enhancer-binding protein ; Zfhep ; Tcf8
Categories	Elisa
Function	Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Specificity	Natural and recombinant Rat Zinc finger E-box-binding homeobox 1
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	ZEB1_RAT
Method Type	Sandwich
Platform	PF00046
Protein Name	Zinc finger E-box-binding homeobox 1
Sensitivity	0.085ng/mL
Sequence	50: MADGPRCKRR ; KQANPRRNNV ; TNYNTVVEAN ; SDSDDEDKLH ; IVEEESVTDA ; 100: ADCEGGVPDD ; ELPTDQTVLP ; GGSDRAGSAK ; NCWQDDVKDD ; ECDSDAENEQ ; 150: NHDPNVEEFL ; QQQDTAVIYP ; EAPEEDQRQG ; TPEASGHDDN ; GTPDAFSQLL ; 200: TCPYCDRGYK ; RFTSLKEHIK ; YRHEKNEDNF ; SCSLCSYTFA ; YRTQLERHMT ; 250: SHKSGREQRH ; VTQSGGNRKF ; KCTECGKAFK ; YKHHLKEHLR ; IHSGEKPYEC ; 300: PNCKKRFSHS ; GSYSSHISSK ; KCISLMPVNG ; RPRSGLKTSQ ; CSSPSLSTSP ; 350: GSPTRPQIRQ ; KIENKPLQEP ; LSVNQIKTEP ; VDYEFKPIVV ; ASGINCSTPL ; 400: QNGVFSGGGQ ; LQATSSPQGV ; VQAVVLPTVG ; LVSPISINLS ; DIQNVLKVAV ; 450: DGNIIRQVLE ; NNQASLASKE ; QEAVSASSIQ ; QGGHSVISAI ; SLPLVDQDGT ; 500: TKIIINYSLE ; QPGQLQVVPQ ; NLKKENPAPP ; KSCKSEKSPE ; DLTVKSEKDK ; 550: SFDGAADEST ; CLLCEDCPGD ; LNALPELKHY ; DPEHPAQPPP ; PAPATEKPES ; 600: SASSAGNGDL ; SPSQPPLKNL ; LSLLKAYYAL ; NAQPSTEELT ; KIADSVNLPL ; 650: DVVKKWFEKM ; QAGQIPGQSL ; EPPSPGPGSG ; NIPAKTEEQP ; QPVDGNEPQE ; 700: DSTRGQSPLK ; MTSSPVLPVG ; SAINGSRSCT ; SSPSPLNLSS ; ARNPQGYSCV ; 750: SEGTQEEPQV ; EPLDLSLPKQ ; QGELLERSTV ; SSVYQNSVYS ; VQEEPLNLSC ; 800: AKKEPQKDSC ; VTDSEPVVNV ; VPPSANPINI ; AIPTVTAQLP ; TIVAIADQNS ; 850: VPCLRALAAN ; KQTILIPQVA ; YTYSATVSPA ; MQEPPVKVIQ ; PNGNQDERQD ; 900: TSSEGVSVED ; QNDSDCTPPK ; KKTRKAENGM ; YACDLCDKIF ; QKSSSLLRHK ; 950: YEHTGKRPHE ; CGICRKAFKH ; KHHLIEHMRL ; HSGEKPYQCD ; KCGKRFSHSG ; 1000: SYSQHMNHRY ; SYCKRGAEDR ; DAMEQEDTGP ; EALPEVLPTE ; LVGARASPSQ ; 1050: ADSDERESLT ; REEDEDSEKE ; EEEEDKEMEE ; LQEDKECENP ; QEEEEEEEEE ; 1100: EEEEEEEEEE ; EAEEAEHEAA ; AAKTGGAVEE ; EAAQQAGSFQ ; QKASGSESKR ; 1109: LSEEKTNEA
Sequence Length	1109
String	Q62947
Sub Unit	Interacts (via N-terminus) with SMARCA4/BRG1.

Uniprot	Q62947
Gene Name	Zeb1
Immunogen Species	Rattus norvegicus (Rat)
Unigene	Rn.10600

Reference	1. "Alternative splicing gives rise to two isoforms of Zfhep, a zinc finger/homeodomain protein that binds T3-response elements." Cabanillas A.M., Darling D.S. DNA Cell Biol.15:643-651(1996) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-1109;ALTERNATIVE SPLICING

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811214	E14970r	96T	$796		Add to Cart

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